CIRFF and the Epichron Research Group of the Aragon Health Search Institute (IIS Aragon) in Zaragoza have been collaborating since 2013 to study the complexity and evolution of multimorbidity and polypharmacy models from real-world data, comparing results emerging from different European settings.

Available results:

Patterns of multimorbidity and polypharmacy in young and adult population: Systematic associations among chronic diseases and drugs using factor analysis

Comorbidity in an Older Population with Type-2 Diabetes Mellitus: Identification of the Characteristics and Healthcare Utilization of High-Cost Patients

Initial Therapy, Regimen Change, and Persistence in a Spanish Cohort of Newly Treated Type 2 Diabetes Patients: A Retrospective, Observational Study Using Real-World Data

Adherencia al tratamiento de hipertensión arterial, hipercolesterolemia y diabetes en población anciana de una cohorte española

Treatment Patterns of Diabetes in Italy: A Population-Based Study